Dr. Stephen Ashwal
Loma Linda University School of Medicine

1970 MD; New York University, New York
1966 BA; New York University, New York

CONTACT
Phone : (909)558-8242
E-mail : sashwal@llu.edu

RESEARCH INTERESTS

Dr. Stephen Ashwal is Distinguished Professor and Chief of the Division of Child Neurology in the Department of Pediatrics at Loma Linda University School of Medicine. He is a graduate of New York University School of Medicine (1966-70), and completed his residency training programs in Pediatrics (Bellevue Hospital, 70-73) and in Child Neurology (University of Minnesota, 73-76).

His research activities have focused on critical care issues in child neurology related to brain death, the vegetative and minimally conscious states, bacterial meningitis, and near drowning; the role of nitric oxide in focal cerebral ischemia; development of animal models of neonatal stroke and the use of proton spectroscopy for outcome prediction after acute CNS injuries.

He has been a member of the Child Neurology Society since 1975 and served as chair of the Scientific Selection, Ethics, Archives and Practice Committee, Councilor from the West, Secretary-Treasurer of the Society, and President (2001-03). Dr. Ashwal edited The Founders of Child Neurology, published on behalf of the Society in 1990, that is a history of the field of child neurology and its major contributors. He served as co-chair (representing the CNS) on The Multi-Society Task Force on the Persistent Vegetative State. He has been active in the development of practice parameters related to child neurology and served as a member of the Quality Standard Subcommittee of the American Academy of Neurology that is responsible for development of guidelines dealing with issues related to the evaluation of children with autism, cerebral palsy, developmental delay, headaches and status epilepticus. With Dr. Kenneth Swaiman and Dr. Donna Ferriero, he served as coeditor of one of the main textbooks in the field of child neurology, Pediatric Neurology: Principles & Practice (2006).


HONORS AND AWARDS

2006 Recipient of the LLU Professional Recognition Award for enhancing LLUMC academic reputation through leadership in worldwide medical organizations and academic publications
2006 Recipient of the Loma Linda University Centennial Vanguard Award in Celebration of the 100th year Anniversary. Given for excellence in Clinical and Research Care
2005 Recipient of the John Stobo Prichard Award and gave the annual Lecture at the Hospital for Sick Children, Toronto, Ontario. Topic, ‘Proton MR Spectroscopy in Pediatric Brain Injury’
2003 Appointed ‘Distinguished Professor of Pediatrics’ at Loma Linda University School of Medicine
2001 Fourteenth Annual Child Neurology Visiting Professor at the Children’s Hospital of San Diego

SELECTED PUBLICATIONS

Chastain CA, Oyoyo U, Zipperman M, Joo E, Ashwal S, Shutter L, Tong K. Predicting Outcomes of Traumatic Brain Injury by Imaging Modality and Injury Distribution. J Neurotrauma. 2009 Mar 24.

Yager JY. Ashwal S. Animal Models of Perinatal Hypoxic-Ischemic Brain Damage. Pediatr Neurol. 2009 Mar;40(3):156-67.

Ashwal S, Obenaus A, Snyder S. Neuroimaging as a basis for stem cell therapy for neontal hypoxic-ischemic brain injury. Pediatr Neurol. 2009 Mar;40(3):227-36.

Golomb MR, Fullerton HJ, Nowak-Gottl U, Deveber G; International Pediatric Stroke Study Group. Male predominance in childhood ischemic stroke: findings from the international pediatric stroke study.Stroke. 2009 Jan;40(1):52-7.

Chinnock RE, Freier MC, Ashwal S, Pivonka-Jones J, Shankel T, Cutler D, Bailey L. Developmental outcomes after pediatric heart transplantation. J Heart Lung Transplant. 2008 Oct;27(10):1079-84.

Galloway NR, Tong KA, Ashwal S, Oyoyo U, Obenaus A. Diffusion-Weighted Imaging Improves Outcome Prediction in Pediatric Traumatic Brain Injury. J Neurotrauma. 2008 Oct;25:1153-62.

Obenaus A, Ashwal S. Magnetic resonance imaging in cerebral ischemia: focus on neonates., Neuropharmacology. 2008;55(3):271-80.

Mathur M, Petersen L, Stadtler M, Rose C, Ejike JC, Petersen F, Tinsley C, Ashwal S. Variability in pediatric brain death determination and documentation in southern California. Pediatrics. 2008 May;121(5):988-93.

Tong KA, Ashwal S, Obenaus A, Nickerson JP, Kido D, Haacke M. Susceptibility weighted magnetic resonance imaging: A review of clinical applications in children. Journal of Neuroradiology 2006 29:9-17.

Hou DA, Tong KA, Ashwal S, Oyoyo U, Joo E, Shutter L, Obenaus A. Diffusion-Weighted MR Imaging Improves Outcome Prediction in Adult Traumatic Brain Injury. J Neurotrauma. 2007;24(10):1558-69.

Wang R, Ashwal S, Tone B, Tian HR, Badaut J, Rasmussen A, Obenaus A. Albumin Reduces Blood-Brain Barrier Permeability But Does Not Alter Infarct Size in a Rat Model of Neonatal Stroke. Pediatr Res. 2007;62(3):261-6.

Badaut J, Ashwal S, Tone B, Regli L, Tian HR, Obenaus A. Temporal and Regional Evolution of Aquaporin-4 Expression and Magnetic Resonance Imaging in a Rat Pup Model of Neonatal Stroke. Pediatr Res. 2007;62(3):248-54.

Morkos AA, Hopper AO, Deming DD, Yellon SM, Wycliffe N, Ashwal S, Sowers LC, Peverini RL, Angeles DM. Elevated total peripheral leukocyte count may identify risk for neurological disability in asphyxiated term neonates. J Perinatol. 2007;27:365-70.

Angeles DM, Ashwal S, Wycliffe ND, Ebner C, Fayard E, Sowers L, Holshouser BA.. Relationship Between Opioid Therapy, Tissue-Damaging Procedures, and Brain Metabolites as Measured by Proton MRS in Asphyxiated Term Neonates. Pediatr Res. 2007 May;61(5 Pt 1):614-21.

Sigmund GA, Tong KT, Nickerson JP, Wall CJ, Oyoyo U, Ashwal S. Multi-Modality Comparison of Neuroimaging in Pediatric Traumatic Brain Injury. Pediatric Neurology, 2007; 36:217-226.



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